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You're probably not more consistent than you were a year ago, two years ago
However, now that semaglutide is no longer on the list, that authorization is revoked
Clinical trials involving investigational medicinal products (CTIMPs) in the UK are governed by the Medicines for Human Use (Clinical Trials) Regulations 2004 (as amended), with safety reporting requirements set out in MHRA and Health Research Authority (HRA) guidance

Peters TJ

Quick Answer: Emerging observational evidence suggests GLP-1 receptor agonists may be associated with reduced depression symptoms, though they are not licensed for mental health treatment and require further research

and inter alia, further down-regulates insulin function and thereby exacerbates Metabolic Syndrome
