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Albiglutide: The HARMONY Outcomes trial (2018) reported a 22% MACE reduction (HR 0.78, 95% CI 0.680.90) in 9463 T2DM patients, driven by reduced MI [18]

Lindqvist, M

Several mechanisms may explain how GLP-1 therapy could theoretically influence bone health, though the clinical significance of these pathways remains under investigation

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Moreover, 1.84 million people have visually threatening DR, about 5% of patients with diabetes

Due to (temporarily) reduced sodium reuptake while continuously promoting glucosuria, these drugs induce a reduction in GFR likely via activation of tubuloglomerular feedback (TGF) that may represent reduced intraglomerular pressure [5]