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Ortiz integrates GLP-1 therapy with the hormonal and nutritional factors that affect its efficacy thyroid status, sex hormones, and insulin sensitivity all influence medication response and are addressed concurrently where relevant

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Ongoing research is now extending the potential of GLP-1 agents into neurological conditions, cardiovascular disease, and non-alcoholic steatohepatitis, broadening the commercial runway further still

PPG neurons display axonal inputs with the most GLP-1R-expressing brain regions and can be activated by the GLP-1 originating from those cells (McLean et al., 2021)

When to speak to your GP If you notice persistent low mood, increased anxiety, difficulty sleeping, or a sense that youre not coping, speak to your GP

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