new glp-1 drug retatrutide Extreme Side Effects Followed Overdose of Unapproved Weight-Loss Weight loss drug retatrutide use

Funding This study was supported by the Kunming Health Science and Technology Thousand Project Talents Project (NO.2021-SW (reserve)-08) and Scientific Research Fund Project of Education Department of Yunnan Province (NO.2024J0277)

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doi: 10.1001/jamapediatrics.2024.3812

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Further detailed investigations of GLP-1R V229A behaviours in beta cells revealed an overall reduction in cholesterol binding under vehicle conditions, which correlated with reduced lateral diffusion, average displacement, and speed of movement across the plasma membrane of the V229A receptor under these conditions