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Wegovy may cause gallbladder problems, including gallstones

doi: 10.1007/s00125-010-2028-x [DOI] [PubMed] [Google Scholar] 168

Freezing can denature the protein structure, rendering the medication ineffective and potentially unsafe

Unlike semaglutide, which targets only GLP-1 receptors, tirzepatide is a dual agonist it activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors simultaneously

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Modelling dynamics in protein crystal structures by ensemble refinement