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Supplementation is another consideration

Structurally, it shares 94% sequence homology with human GLP-1 but includes two critical modifications: the substitution of amino acids to prevent enzymatic degradation by Dipeptidyl Peptidase-4 (DPP-4), and the addition of a C-18 fatty di-acid side chain

While NZ doesnt yet fund metformin for MS, the MACSiMiSE-BRAIN trial overseas is exploring its neuroprotective potential in progressive MS

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Look TM, et al