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The glycosuria induced by these medications creates a glucose-rich urinary environment that can promote genital mycotic infections (thrush) in 1015% of patients, particularly women

Guyatt, G

The investigation specifically showed that these drugs did not increase the risk of any fractures, confirming their safety profile in clinical practice ( 4.6 Ophthalmological effects 4.6.1 Glaucoma GLP-1R agonists exhibit anti-inflammatory and neuroprotective properties, suggesting they could also be beneficial in neurodegenerative diseases ( A recent registry-based case-control study, summarized in Table 2 , involving 1,961 patients found that the use of GLP-1R agonists is linked to a lower risk of glaucoma (Sterling et al., 2021 (79)
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Keywords: Glucose-dependent insulinotropic polypeptide (GIP), Incretin, Obesity, Diabetes Graphical Abstract Introduction Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are incretins, which are peptide hormones released from enteroendocrine cells into circulation in response to nutrient ingestion to potentiate glucose-stimulated insulin secretion [1-3]
