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The authors connect this to something known as the rate hypothesis in addiction research: the faster a substance hits the brain, the stronger and more rewarding it feels

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Patients who were treated for type 2 diabetes with a GLP1RA or DDP4i during this period (n=1,080,993), were identified

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Retatrutide is not yet FDA-approved, but clinical trial data demonstrate a specific dose escalation protocol starting at 2 mg weekly with gradual titration t...