how do glp 1 lower blood sugar GLP-1 Receptor Agonists as Treatments for Type 2 Diabetes Glucagon-like peptide-1 receptor: mechanisms and
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For instance, it turns glucose into usable energy
Activation of GLP-1R induces an increase in intracellular Ca 2+ in 40% of NTS astrocytes, while selective inhibition of astrocyte function in NTS abolishes exendin-4-induced inhibition of food intake (Reiner et al., 2016)
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doi: 10.3389/fnins.2022.970925 91
For patients using insulin or sulfonylureas, reducing their doses by 25% when starting GLP-1 therapy can help avoid hypoglycemia
10.2337/diacare.28.5.1092 30 DeYoungM
