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Here, we summarize that activation of GLP-1 receptor (GLP-1R) suppresses food intake and induces postsynaptic depolarization of membrane potential and/or presynaptic modulation of glutamatergic or GABAergic neurotransmission in brain nuclei located within the medulla oblongata, pons, mesencephalon, diencephalon, and telencephalon

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When to Seek Medical Attention According to prescribing information, patients should contact their healthcare provider immediately if experiencing: Severe abdominal pain that does not go away Signs of allergic reaction (swelling of face, lips, tongue, or throat

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When you eat, GLP-1 helps your pancreas release insulin to lower blood sugar, and it also slows down how quickly food leaves your stomach, making you feel fuller for longer