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GLP1 Wegovy (semaglutide) and GIP Mounjaro (tirzepatide) injections are not currently licensed as smoking-cessation treatments

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Although lifestyle intervention, sodiumglucose cotransporter 2 (SGLT2) inhibitors, incretin-based therapies, and liver-directed treatments have broadened the therapeutic framework for this overlap phenotype, prospective evidence specifically addressing patients with coexisting MASLD and HFpEF remains limited

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1 For those individuals who have insulin resistance (insensitivity) and/or are diagnosed with T2DM, GLP-1 receptor agonists are oral or injectable medications that mimic this natural hormone and may be recommended to help manage blood sugar in some patients