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For instance, for the standard q1wk dosing, the model predicts steadystate body weight reductions of 17%, 21%, and 23% for tirzepatide at 5 mg, 10 mg, and 15 mg, respectively (which is in good agreement with clinical data 8 , 10 )

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Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial

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