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Summary The proposed integrated approach underscores the importance of personalised nutritional strategies guided by patient-specific metabolic, hormonal, and microbiota profiles, and calls for effective multidisciplinary collaboration among nutritionists, endocrinologists, and behavioural health professionals to optimise therapeutic outcomes

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This approach highlights how nutritional substrates and metabolic cofactors may influence physiological resilience during sustained pharmacological weight reduction

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Foods that support short-chain fatty acid production-When gut bacteria feed on dietary fibre, they produce postbiotics that contain short-chain fatty acids (SCFA) such as acetate and butyrate