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Consistently, administration of GCGR antagonists in patients with T2D resulted in decreased glucose levels (35) but also increased body weight providing human support for glucagon receptor agonism (36)

It is also known by its generic name, Tirzepatide, a new injectable medication developed by Eli Lilly

Wegovy is FDA-approved for obesity and for cardiovascular risk reduction

Nguyen, U

While individual risk can be modified by genetic influences, population risk and trends in obesity over time are predominantly driven by lifestyle trends related to cultural, community, and environmental factors

doi: 10.1093/ije/dyy258