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doi: 10.1177/2042018821997320 35 ZinmanBWannerCLachinJMFitchettDBluhmkiEHantelSet al

GLP-1RA (such as exendin-4) treatment can reduce the size of MI impacted cardiac volume in rats, inhibit ventricular dilation, myocardial fibrosis and hypertrophy in vivo [72]
Steroids induce insulin resistance by directly interfering with signaling cascades, mainly the GLUT4 transporter, within muscle cells, with the subsequent 30%-50% reduction in insulin-stimulated glucose uptake and a 70% reduction in insulin-stimulated glycogen synthesis[24,25]

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One may speculate that GIP-mediated glucagon secretion underlies this phenomenon

[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Signorile A, et al