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Similarly, interrupted use was associated with increased MACE risk, with IRRs of 1.12 for one year and 1.16 for two years of interruption, with effect sizes differing modestly depending on prior treatment duration

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Timosaponin AIII is a steroidal saponin extracted from Anemarrhena asphodeloides

However, Ruminococcaceae usually acts as potential probiotics to ameliorate colitis, stressing more studies to clearly understand the effects of intestinal microflora in maintaining the intestinal epithelial layer integrity and the manifestation of UC