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This four-weekly step-up mirrors the escalation approach used in the phase 2 trial, where a lower 2mg starting dose helped mitigate early GI side effects

Youll stay at that level each time your dose increases for at least 4 weeks

Some people find this feels "weaker" initially because the peak concentration is lower, even though the total weekly drug exposure is similar

Overview of Semaglutide: Mechanism and Uses Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that mimics the effects of the natural hormone GLP-1 in the body

Furthermore, the market for GLP-1 medications is expected to continue growing in the coming years

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