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Stimulation of -cell proliferation secondary to stimulating GLP-1R is usually only observed in young animals (during periods characterized by preserved proliferative capacity), and not in older rodents [548]

Russ Physiol J 108(9): 10771093

Table 1 summarizes the characteristics and main findings of the 11 included studies

GLP-1 agonists directly bind to and activate GLP-1 receptors on pancreatic cells, while berberine works primarily through AMPK activation and does not directly interact with GLP-1 receptors

doi: 10.1161/hyp.0000000000000202

Marketing materials - from any platform - should not substitute for that clinical conversation