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A total of 526 (61.52%) of all enrolled patients developed GISEs, of which 14 (1.64%) discontinued GLP-1RA treatment due to intolerance to GISEs

Avoiding high-fat and spicy foods, citrus, chocolate, and caffeine can reduce acid irritation of the esophageal lining

Some reports suggest that the slowed digestion caused by GLP-1s may affect the absorption of oral birth control pills, potentially leading to breakthrough ovulation

Safety Considerations and Potential Side Effects Semaglutide is generally well-tolerated, but common side effects include nausea, vomiting, diarrhea, and constipationmost of which diminish as your body adapts during the first few weeks of treatment

An all-natural supplement, scientifically developed to help you feel fuller for longer

The Cochrane Collaborations tool for assessing risk of bias in randomised trials