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Even the encouraging early research does not suggest these medications are a cure, and results vary

Effectiveness: In a study of 2,539 adults with obesity or overweight plus at least one weight-related medical condition (excluding diabetes), the average weight loss at 72 weeks was 15% with 5 mg weekly doses of tirzepatide, 19.5% with 10 mg doses, and almost 21% with 15 mg doses

Adding to the pressure on J&J is a September 2024 announcement from Cignas Evernorth Health Services that it will offer an interchangeable biosimilar alternative to Stelara at $0 out-of-pocket

Among women who used a GLP-1 1 year before delivery, 11% developed gestational diabetes vs

Comparing it to alternatives like WW (Weight Watchers), MyFitnessPal, and Calibrate helps put the cost in perspective

If you develop new symptoms suggestive of hyperglycaemia or your home glucose readings consistently exceed your target range, contact your GP or diabetes team promptly