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Novo Nordisk has officially filed a New Drug Application (NDA) with the FDA for CagriSema, a once-weekly injectable obesity therapy that combines amylin and GLP-1 mechanisms

This helps individuals feel fuller faster and for a longer period, leading to reduced caloric intake

Participants who faced access issues reported a 13.7% weight loss within 12 months and a 14.9% loss within 24 months, on average

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Why Direct-Pay GLP-1 Therapy Bypasses Insurance Tiers Direct-pay compounded GLP-1 options sidestep insurance tier systems entirely by having patients pay out-of-pocket on a predictable monthly basis

Mosenzon O, Blicher TM, Rosenlund S et al (2019) Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial