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This work was supported by the Lundbeck Foundation (fellowship R238-2016-2859), the BioInnovation Institute (grant number NNF20OC0063538) and the Novo Nordisk Foundation (grant numbers NNF17OC0026114 and NNF22OC0073778)

I started GLP-1 because I thought it would make my life easier, since I feared continuing my pattern of compulsive eating and losing control over my body

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27 Hence, using Ile 12 in tirzepatide seems not to weaken its GLP-1 activity and to strengthen its GIP activity

The company is also pursuing other approaches, including a drug called CagriSema that combines semaglutide the active ingredient in Ozempic and Wegovy with cagrilintide, which targets another hormone called amylin