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Additionally, proteolytic degradation is a major challenge in peptide-based therapeutics, as it results in short half-life, low bioavailability, rapid clearance, and ultimately reduced therapeutic efficacy
Basal insulin consistently increases insulin levels and lowers FPG
Options include: Topical azole antifungals : Clotrimazole, miconazole, or tioconazole creams or suppositories used for 1-7 days depending on formulation strength Oral fluconazole : A single 150 mg dose for uncomplicated infections, available by prescription Combination therapy : Topical treatments for external symptoms plus oral medication for internal infection Pregnant patients should use topical azole therapy for 7 days and avoid oral fluconazole
Research continues into its effects on hepatic fat, lipid profiles, and insulin sensitivity
Moitra M, Santomauro D, Collins PY, Vos T, Whiteford H, Saxena S, et al
Lixisenatida (Adlyxin): Inyeccin subcutnea diaria
