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In TriNetX, after defining the cohorts, index dates, outcomes, and relevant covariates that could serve as potential confounders, the platform creates a covariate matrix by capturing each variable for individual patientstypically within one year before the index date

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The plan is easy to follow

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Song, G

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Yet, about 30% of PV inspections (FDA/EMA) uncover serious issues

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While genetic variants do not predict exact side effect occurrence, they may help provide context for individual tolerability patterns and support more informed conversations with your provider about tirzepatide suitability

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