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Many proteins, including small guanosine triphosphatases (GTPases) (Rab3a, Rab27a, Rab4, Ras homology family member A [RhoA], Ras-related C3 botulinum toxin substrate 1 [Rac1], and cell division cycle 42 [Cdc42]), cytoskeletal proteins (myosin heavy chain, -actin, -actin, -actin, and actin-binding protein filamin A), extracellular matrix protein fibronectin, and histones have been described as substrates for serotonylation [62]
Ozempic, Rybelsus or similar medications can cause alike adverse effects
Patients should be counseled about these risks and monitored appropriately if concurrent use is pursued
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Al-Badri MR, Azar ST
