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Key secondary endpoints include change in waist circumference, blood pressure, lipid levels and patientreported health outcomes, as well as glycemic parameters in participants with T2D
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Overall, these findings show that GLP-1R recycling is influenced by persistence of agonist binding within the endosomal compartment, resulting in enhanced insulin-releasing properties of fast-dissociating agonists which maintain an adequate population of cell surface receptors over prolonged periods
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Supporting this, Saxena et al
