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The blood pressure lowering effects of glucagon-like peptide-1 receptor agonists: A mini-review of the potential mechanisms

Emerging Frontiers in GLP-1 Therapeutics: A Comprehensive Evidence Base (2025)

Moreover, GLP-1 RAs physiological effects on food intake were dependent on AMPA receptor, but not NMDA receptor, activity

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In this global registration trial, where 84.0% of participants had a baseline BMI of 35 kg/m, each dose of retatrutide (9 mg and 12 mg) met all primary and key secondary endpoints, delivering significant weight loss and improvements in pain and physical function at 68 weeks using both the efficacy and treatment-regimen estimands

[DOI] [PubMed] [Google Scholar] 133.Laurenti M.C., Dalla Man C., Varghese R.T., Andrews J.C., Rizza R.A., Matveyenko A., De Nicolao G., Cobelli C., Vella A
