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doi: 10.1093/ajcn/72.3.796 [DOI] [PubMed] [Google Scholar] 37

Novel subgroups of type 2 diabetes and their association with microvascular outcomes in an Asian Indian population: a data-driven cluster analysis: the INSPIRED study

The EMPEROR-Preserved and DELIVER trials investigated the impact of empagliflozin and dapagliflozin, respectively, on cardiovascular outcomes in patients with mildly reduced or preserved ejection fraction

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The canonical cAMP/PKA/CREB pathway for gene transcription lies downstream of ligand binding to an appropriate G-protein coupled receptor, causing cAMP production, that in turn activates PKA to directly phosphorylate CREB resulting in histone modification and increased transcription (143, 144)