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Dry mouth is a documented side effect reported by some patients taking GLP-1 receptor agonists like semaglutide

Shima Hadidchi, MD in Apple Valley, CA For Lasting Results.

This means that its natural effect in the joint is likely to be limited
This review also highlights a possible crosstalk between autophagy and the GLP-1/GLP-1R axis in the treatment of diabetic angiopathy.
