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Entero-endocrine-osseous axis : gastrointestinal hormones as substrates for DPP-4 The initial observation that patients receiving long-term parenteral nutrition develop osteoporosis and osteomalacia raised suspicion about the lack of stimulation for the secretion of incretin hormones in this mode of nutrition and a potential connection between these hormones and bone metabolism [42]

In this trial, those who received Wegovy had a 20% reduction in risk of major adverse cardiovascular events compared to those who received the placebo

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Additionally, factors secreted by retinal cells, like IL-6, promote the proliferation of different retinal cell types, contributing to the formation of new blood vessels and the progression of diabetic retinopathy (84)

The research team examined rates of newly diagnosed breast cancer in two groups: the full study population and a smaller matched cohort of 30,528 women

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