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Clinical trial evidence supports Retatrutides potential relevance to PCOS-related hyperinsulinemia by leveraging findings from advanced incretin-based therapies

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Participants in the tablet trial lost an average of 13.6% of body weight at 64 weeks, while those in the injection trial lost 14.9% at 68 weeks

A Danish nationwide cohort study also reported a lower risk of corticosteroid use and hospitalization in IBD patients with DM2 undergoing GLP-1 RAs rather than other antidiabetic treatments (98)

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