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Tirzepatide is the first in a class of drugs called dual GLP-1/GIP receptor agonists that activate the receptor for another gut hormone, glucose-dependent insulinotropic polypeptide (GIP), in addition to the GLP-1 receptor

J Am Acad Dermatol 2007;56:901-16

The DPP-4 cleavage at postproline peptide bonds inactivates peptides and/or generates new bioactive peptides, thereby regulating diverse biological processes

Starting GLP-1 therapy only to stop it two months before trying to conceive may not provide a long enough treatment window to achieve meaningful results

While these strategies help optimize patients for anesthesia-related care, they do not eliminate all risks for GLP-1 medication-related perioperative complications

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