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Research progress on the GIP/GLP-1 receptor coagonist tirzepatide, a rising star in type 2 diabetes

Almaqhawi A, Alokley A, Alamri R et al (2025) Effectiveness of topiramate versus Acetazolamide in the management of idiopathic intracranial hypertension: asystematic review and Meta-Analysis

This limits statistical power for further analyses, so there are few other publications from SUSTAIN-6 (Box 2)

Forest plot of Lixisenatide versus comparators on the risk of overall Respiratory diseases

There are currently no robust studies showing that smaller doses deliver the same cardiovascular or metabolic advantages, or even that they work consistently at all

It may also be used in people with a BMI of 27 or higher who have other weight-related medical conditions, such as type 2 diabetes or high blood pressure