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Losing fat while preserving lean mass is very different from simply losing weight

Her nurse practitioner told her to stop taking Ozempic in October 2023 because of severe side effects, including persistent vomiting

Despite this, Novo Nordisk has been heavily advertising this medication, claiming it can help individuals lose weight and keep it off
These effects are often the result of slowed gastric emptyingthe very mechanism that increases satiety and reduces food intake

A characteristic feature is the loss of interstitial cells of Cajal, likely secondary to immunological changes, such as a shift from protective M2 to M1 macrophages and impaired regulation of haem oxygenase-1, leading to oxidative stress

[DOI] [PubMed] [Google Scholar] 650.Asmar A., Asmar M., Simonsen L., Madsbad S., Holst J.J., Hartmann B
