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GLP-1 oxidates fatty acids and reduces its influx into hepatocytes, inhibiting NAFLD

Now the confirmed mechanism of metformins hypoglycemic action is to inhibit hepatic gluconeogenesis and reduce hepatic glucose output through both AMPK-dependent (Song et al., 2001

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Therefore, follow-up strategies focus on effectiveness rather than frequency alone

Broughton, K

The incidence of serious AEs was not significant, and the most frequently reported AEs were associated with the gastrointestinal system