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Although a modest benefit of GLP-1RA in preventing HF hospitalizations has emerged, this finding deserves to be confirmed in mechanistic studies

doi: 10.1016/j.neubiorev.2021.03.029

[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Majumder D

Given the natural fluctuations in hormone levels and the intricate rhythms of human physiology throughout the day and over a persons lifetime, there is concern about the uncertain health ramifications of sustained elevation of incretin activity over decades of treatment

Found incorporates diet, lifestyle, and prescription GLP-1s, plus the program is said to consider genetics and hormonal differences as well

The data just isnt in yet
