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Description
Across the orforglipron clinical program, cases of pancreatitis have been rare and have not exceeded the background rate expected in the study populations

September 9, 2024

Even modest losses of true skeletal muscle, particularly if accompanied by reductions in strength or power, may have outsized consequences for function and healthspan
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10.1016/S0140-6736(08)61246-5 [DOI] [PubMed] [Google Scholar] 49

Moreover, clinicians should monitor for rare but serious risks such as pancreatitis or gallbladder disease
