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The most well-known GLP-1 drugs include: Ozempic (semaglutide) - FDA-approved for Type 2 diabetes Wegovy (semaglutide) - FDA-approved for chronic weight management and cardiovascular risk reduction Mounjaro (tirzepatide) - FDA-approved for Type 2 diabetes Zepbound (tirzepatide) - FDA-approved for chronic weight management and obstructive sleep apnea Foundayo (orforglipron) - a newer oral GLP-1 option Here's an important detail many people miss: Ozempic and Wegovy contain the exact same active ingredient (semaglutide), made by the same manufacturer (Novo Nordisk)

Additional evidence has indicated that GLP-1RAs elevated circulating irisin levels and BDNF (47, 48)

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These findings underscore the complex interplay between sex, diet, and GE2 efficacy in middle age, emphasizing the need for tailored therapeutic strategies

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