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The dark blue circles in the terminal portion of tirzepatide are amino acids from exenatide, a protein-derived peptide (exendin-4) present in the venom of the Gila monster ( Heloderma suspectum ) and known to activate the receptor GLP-1

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To support this treatment, patients are encouraged to maintain a balanced diet, exercise regularly, establish a consistent sleep cycle, and maintain continuous communication with their provider

They correlate with speed of weight loss, not with duration of treatment

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