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Clinical Evidence on Combined TRT and GLP-1 Use Retrospective data from men's health clinics indicate that concurrent TRT and GLP-1 therapy is well-tolerated when both medications are dosed appropriately

Lean mass as with any weight-loss intervention, some lean mass was lost
Motus (oral), for example, reported tolerable safety outcomes in its human clinical trial context

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Its very likely that GLP-1s will continue to be game changers in obesity and metabolic medicine, with benefits far outweighing risks
