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The use of GLP-1 RAs may be more effective in PD patients with insulin resistance or T2D, due to overlapping metabolic and neuroinflammatory pathways that may enhance therapeutic responsiveness

This occurs because gut bacteria are actively fermenting the prebiotic fiber, and the resulting gas production peaks before the microbiome stabilizes around its new bacterial balance

Nausea, diarrhea, constipation, and lack of appetite are the most common

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Pharmacology 2.1

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