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The weight loss from GLP-1 agonism derives from appetite suppression and possibly enhanced satiety signals

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One consideration is that if any injection-site reactions occur (redness, swelling, mild bruising), you won't notice them until morning

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Sterile water for injection does NOT contain a preservative and should only be used for single-dose reconstitution, as it provides no protection against microbial contamination after the first needle puncture