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104 The most common side effect for both GLP-1RAs and metformin is moderate gastrointestinal discomfort, which can be soothed by gradual dose titration, eating small portions meals but with a higher frequency, and avoiding some compounds, including stimulant or secretory substances (caffeinated beverages, spices) and those known to cause relaxation of lower esophageal sphincter (fatty, fried or processed foods, chocolate, tomato, mint)

The BALANCE Model will empower more Americans to live healthier lives by expanding access to GLP-1s that have shown to be a powerful tool against the development of diseases, such as diabetes, cardiovascular disease, and other metabolic conditions, which can negatively affect a persons long-term health, CMMI Director Abe Sutton said in the press release

Paul Cordts said in a statement

The other authors declare no conflicts of interest relevant to this paper
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