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Stimulant laxatives (like senna or bisacodyl) can be used occasionally, but long-term reliance may reduce effectiveness and cause dependency

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No studies have been performed to determine safety of GLP-1s in patients who are pregnant or breastfeeding

Blood sugar management may need adjustment during the break period

It is also worth noting that these effects of liraglutide in OVX animals occurred relatively quickly, with positive outcomes observed after just four weeks of treatment, consistent with in vitro data [57]
