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[33] Based on the clinical dosing regimen (2.5 to 5 mg TZP weekly), we estimated that a depot designed to release TZP continuously over four months in a rat model should contain approximately 4.5 mg of drug within a subcutaneously injectable volume (typically 0.5 to 2 mL)

Researchers running shorter cohorts at lower doses generally prefer the 20mg or 10mg formats

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Several SRMAs reported changes in blood pressure, body mass index (BMI), and CRP, but with limited statistical significance