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Treatment with the sodiumglucose cotransporter 2 inhibitor dapagliflozin was recently shown to reduce aortic stiffness, systolic BP and pulse pressure during exercise after just 24 weeks, and these changes were correlated with reductions in left ventricular filling pressures 25

In plain English, this means the medication mimics two hormones naturally produced by your body

At industrial scale, it is a dirty process, Lax says

For individual compounds, use the narrower article when available

1 Type 2 diabetes can be challenging enough to manage without the added risk of chronic kidney disease, and I have seen in my own practice that patients with type 2 diabetes and chronic kidney disease need extra support from medications that may have a profound clinical impact by lowering the risk of major kidney and cardiovascular outcomes, said Richard E