haleon plc glp-1 receptor agonist medications “Weighing In” on Agonists for People With HIV Holding GLP-1 Agonists Prior to

As GLP-1 RAs are contraindicated for people with gastrointestinal disease, pancreatitis, or a family history of mutations in multiple endocrine neoplasia type 2/medullary thyroid carcinoma (MEN2/MTC), SGLT2i is the preferred treatment for these patients groups

Randomized, double-blind, phase 3 trial of triple therapy with dapagliflozin add-on to saxagliptin plus metformin in type 2 diabetes

There have also been studies suggesting a slightly elevated risk of thyroid C-cell tumors.

Supplementary Section 3)

Belfort R, Harrison SA, Brown K, Darland C, Finch J, Hardies J, et al

Other companies (e.g., Pfizer, Roche, AZ) have their own GLP-1-related programs, but none have launched major products yet