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Similarly, at week 12, reduction in HbA1c from baseline was significantly greater with DAPA + SITA + MET ER compared to SITA + MET SR ( p = 0.0006) and DAPA + MET ER ( p = 0.0276)

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In a controlled crossover feeding study, a high-GI meal selectively increased activation in reward and craving regions four hours postprandially compared with an isocaloric low-GI meal, independent of palatability [26]

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However, many patients find their desire for alcohol decreases along with appetite generally

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