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4 , 29 More recently, dual GLP-1/glucagon and triple GLP-1/glucagon/glucose-dependent insulinotropic polypeptide (GIP) RAs have been developed to achieve more pronounced weight loss and have demonstrated larger BP reductions than single GLP-1 RAs in early-phase RCTs

Table of Contents How Retatrutide Works and Its Known Side Effects Retatrutide is an investigational triple receptor agonist targeting GLP-1, GIP, and glucagon receptors

10.1210/en.2013-1934 47
