glp 1 inhibitors mechanism of action GLP1-GIP receptor co-agonists: a promising evolution in the treatment type 2 diabetes | Acta Diabetologica The Impact of GLP-1 Receptor
Description
Early clinical trials evaluating the efficacy of GLP-1 receptor agonists reported a slightly increased risk of acute pancreatitis with these medications versus placebo or conventional treatment

20 TECOS (2015) did not show an increased risk of HF in patients taking sitagliptin for treatment of type 2 diabetes

doi: 10.1159/000485776 32 ShahZKampfrathTDeiuliisJAZhongJPinedaCYingZet al

1 In clinical trials, patients with higher antibody titers have been seen to have smaller reductions in A1C compared to those with low or negative titers

CI=confidence interval

When your body produces GLP-1, it signals your pancreas to produce insulin, slowing the emptying of your stomach
